The ULACAN database results (Fig. 1B) showed that in the vast majority of these cancers, STAT3 proteins were overexpressed (Fig. 1C), such as in breast invasive carcinoma (BRCA, P = 4.09E−05), uterine corpus endometrial carcinoma (UCEC P = 2.89E−02), lung adenocarcinoma (LUAD P = 3.42E−03), head and neck squamous carcinoma (HNSC P = 4.56E−16), pancreatic adenocarcinoma (PAAD P = 2.77E−03), and glioblastoma multiforme (GBM P = 1.19E−22). Here, STAT3 is linked to lung adenocarcinoma.