In DFS (Fig. 2C, D), patients with kidney chromophobe (KICH, P = 0.05, HR = 4.3), brain lower grade glioma (LGG, P = 0.0021 HR = 1.6), and uveal melanoma (UVM, P = 0.037 HR = 2.7) with high levels of STAT3 expression had a significantly worse median survival time than those with low expression in the vast majority of cases. Here, STAT3 is linked to uveal melanoma.