The RNA-sequencing expression level of immunomodulatory genes like CD274 (PD-L1, Programmed Cell Death), CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4), IDO1 (Indoleamine 2,3-Dioxygenase 1), and LAG3 (Lymphocyte Activating 3) are altered in breast, glioblastoma, head and neck, liver, ovarian, prostate, sarcoma, stomach, and uterine tumors (Supplementary Fig. 9). The gene discussed is CD274; the disease is glioblastoma.