For instance, METTL3-mediated m6A modification on the 5’UTR of NUCB1 (encoding a calcium-binding protein) mRNA via YTHDF2 (YTH N6-methyladenosine RNA binding protein 2) reader protein in pancreatic adenocarcinoma was associated with poor prognosis. Here, YTHDF2 is linked to pancreatic adenocarcinoma.