PTK2 and neoplasm: To determine whether Psmb9 upregulation in FAK-/- cells contributed to the defect in tumour growth, 0.5×106 FAK-wt, FAK-/-, FAK-/-Psmb9C2 or FAK-/-Psmb9C6 cells were implanted into the pancreas of C57BL/6 mice and tumours harvested and weighed after 2 weeks (online supplemental figure 3E).