Immunohistochemical staining of FAK-/- and FAK-/-STAT3shRNA tumour sections using an anti-CD8 antibody also confirmed the infiltration of CD8 T-cells within the tumour mass (figure 7F—left and J), while an anti-granzyme-B antibody showed positive intratumoural staining indicative of ongoing CD8 T-cell activity (figure 7F—right and K). Here, GZMB is linked to neoplasm.