In particular, splenic cDC expressed higher levels of CD40, CD80, and CD86 from 4 h to 48 h post-infection compared with 0 h, especially at 4 h, with values of 21.1% ± 5.3 (p = 0.028), 48.1% ± 5.0 (p = 0.018), and 36.2% ± 3.1 (p = 0.009), respectively. Here, CD40 is linked to infection.