In another study on the BV2 microglial cell PD model, it was shown that neuroinflammation is mediated by an increase in ROS and NOD-like receptors (NLR) family pyrin domain containing 3 (NLRP3), and urolithin A, due to its effect on mitophagy, reduced neuroinflammation and provided a neuroprotective effect [84]. The gene discussed is NLRP3; the disease is Parkinson disease.