Actually, a loss-of-function mutation of vacuolar protein sorting 11 (VPS11), as the core subunit of complexes of class C core vacuole/endosome tethering (CORVET) and homotypic fusion and vacuole protein sorting (HOPS), specifically causes hypomyelinating leukodystrophy 11 (HLD11), which is a genetic oligodendroglial cell disease [26]. The gene discussed is VPS11; the disease is hypomyelinating leukodystrophy 11.