The resultsshowed that in HCT 116p53–/– the amountsof ABCB1 and ABCC9 mRNAs were lower than in uL3ΔHCT 116p53–/– at all time points (Figure 2d,e), whereas the amount of ABCC11 mRNA didnot change significantly in uL3-silenced CRC cells compared to thatof parental cells, demonstrating that the uL3 status did not affectABCC11 mRNA stability (Figure 2f). The gene discussed is ABCB1; the disease is colorectal carcinoma.