Dysregulation of the glycoprotein occurs mainly in the Lauren diffuse type and leads to gastric epithelial cell dysfunction and tumor progression and invasion [35, 36].β-Catenin, in turn, is an intracellular scaffold protein that interacts with adhesion molecules, such as E-cadherin, with transmembrane mucins, such as mucin 1, with signalling regulators and with epigenetic or transcriptional regulators [37, 38]. This evidence concerns the gene MUC1 and neoplasm.