When compared with participants with Lp(a) levels corresponding to the lower tertile (≤4.8 mg/dL), patients with Lp(a) levels corresponding to the upper tertile (>40.9 mg/dL) had a higher risk of aortic valve calcification (OR 1.57; 1.02–2.42) [16]. This evidence concerns the gene LPA and aortic valve calcification.