Furthermore, Li et al. [70] reported rearranged C-MYC, BCL-2 and BCL-6 genes in 29, 25 and 50% of tested cases, respectively, and stated that C-MYC rearrangement frequency was found significantly higher in PB-DLBCL, NOS (29%) compared to non-osseous de novo DLBCL, NOS (12%) and nodal DLBCL, NOS (9%). This evidence concerns the gene MYC and diffuse large B-cell lymphoma.