In a larger, recent retrospective study, Meng et al. specifically targeted ATRX status in 123 patients diagnosed with gliomas (World Health Organization grades II–IV) using radiomics analysis, showing that radiomic features derived from preoperative MRI facilitate the efficient prediction of ATRX status in gliomas, achieving an AUC for ATRX mutation (ATRX(−)) of 0.84 (95% CI: 0.63–0.91) on the validation set, with a sensitivity, specificity, and accuracy of 0.73, 0.86, and 0.79, respectively [79]. This evidence concerns the gene ATRX and central nervous system cancer.