The cytotoxic effects of PM2.5 on normal lung and lung cancer cells were evaluated by short‐term 24‐h exposure using the normal lung fibroblast cell lines MRC5 and IMR90 and lung cancer cell lines A549 (EGFR wild‐type) and H1975 (EGFR L858R+T790M). Here, EGFR is linked to lung cancer.