In addition, after sacrificing the mice, a qPCR analysis showed significantly increased Lcn2 expression in the tissues (eWAT, iWAT, and Gast) of cachexia model mice (Fig. 1H); eWAT, iWAT, and Gast undergo atrophy in cachexia [24, 25]. The gene discussed is LCN2; the disease is Cachexia.