Gene-based output (Supplementary Table 1) suggested two genes encoding mitochondrial proteins on chromosome 15; MRPL46 associated with depressive disorders (minimum p = 6.24 × 10−5)49,50 and MRPS11 (minimum p = 3.16 × 10−6) linked to body-mass index (BMI)51. Here, MRPS11 is linked to depressive disorder.