The expression of YTHDF2 was negatively correlated with CDKN2B and SPOCK2 mRNAs in multiple pediatric glioma datasets (Supplementary Fig. 8c, d), supporting the pathological role of YTHDF2 negatively regulating CDKN2B and SPOCK2 transcripts in glioma development. The gene discussed is SPOCK2; the disease is central nervous system cancer.