As expected, the majority of HN279 cancer cells expressed MDK (Fig. 6d and Supplementary Fig. 6j–l), together with a number of genes associated with the pre-nodal phenotype (eg SNAI2, AXL, STAT2) that were unaffected by ICB (Fig. 6e and Supplementary Fig. 6m). The gene discussed is MDK; the disease is cancer.