IL6 and Sepsis: In conclusion, it has been proven that our PLNPscan be used as nanoprobes for the detection of IL-6 in clinical applicationssuch as the sepsis, where healthy adults without inflammation havelow IL-6 concentrations (<10 pg·mL–1)54,55 compared to septic episodes where the levels of this cytokine candramatically increase.54,56 However, it should be noticedthat the negative control ([IL-6] = 0 pg·mL–1) showed some signal, which is likely due to some nonspecific absorptionof the PLNPs-Abd nanoprobes.