In the cohort of prevalent PBC patients, those with cirrhosis (n=13) had higher median sCD163 levels (5.39 mg/L, IQR: 3.98–5.67) than those without cirrhosis (n=87, median=3.21 mg/L, IQR: 2.67–4.47), p<0.001. The gene discussed is CD163; the disease is primary biliary cholangitis.