The epitope for ANDV-5 maps to the α–3 and α–4 helices, while ANDV-34 targets domain B. Both sites of vulnerability do not overlap with the epitopes determined for previously described Gn-targeting mAbs, HTN-Gn1 and nnHTN-Gn2 (Rissanen et al., 2017; Rissanen et al., 2021). This evidence concerns the gene GYG2 and hypertensive disorder.