Overall, we retrospectively screened 256 patients with NMDA‐autoantibody‐associated AE, 76 with LGI1‐LE, 21 with GABAb‐autoantibody‐associated LE (GABAb‐LE), 13 with GAD‐autoantibody‐associated LE (GAD‐LE), 6 with CASPR2‐autoantibody‐associated LE (CASPR2‐LE), and 4 with metabotropic glutamate receptor 5‐autoantibody‐associated AE (mGLUR5‐AE), as well as patients with anti‐amphiphysin (n = 7), anti‐Hu (n = 3), ‐Yo (n = 2), ‐CV2 (n = 2), and anti‐AMPAR encephalitis (n = 1). The gene discussed is CNTNAP2; the disease is acrodermatitis enteropathica.