Notably, the density of CD8+ T cells was negatively correlated with tumor size, histologic grade, TNM stage, lymph node metastases, and CA19-9 concentration, whereas the densities of CD133+ CSCs and TB were positively correlated with tumor size, histologic grade, TNM stage, lymph node metastases, and CA19-9 concentration. This evidence concerns the gene PROM1 and neoplasm.