The common mutation genes included IDH1, TP53, ATRX, CIC, TIN, EGFR, and PTEN. Notably, the GMRG expression clustering of gliomas was significantly associated with the mutational status of IDH genes (Figures 2D, J), which has been a known determinant for the survival outcome of patients with glioma. The gene discussed is PTEN; the disease is central nervous system cancer.