To further elucidate the prognostic value of GMRG expression clusters in this context, we split the TCGA cohort according to the IDH mutational status and found that the cluster 1 gliomas had a significantly better outcome compared to cluster 2 gliomas in both IDH-mutant and IDH-wildtype gliomas (Figures 2K, L). The gene discussed is IDH1; the disease is glioma.