According to the GSVA results, we found a few mechanisms involved in immunity affected in CAD, such as IL-6/JAK/STAT3 SIGNALING, INFLAMMATORY RESPONSE, TNFA SIGNALING VIA NFKB, PI3K AKT MTOR SIGNALING and IL2 STAT5 SIGNALING (Figure 1). The gene discussed is NFKB1; the disease is coronary artery disorder.