Univariate cox analysis of PFI showed (Figure 4C) that RBP1 was a risk factor for patients with pancreatic adenocarcinoma (PAAD), KIRC, LGG and a protective factor for patients with pheochromocytoma and paraganglioma (PCPG) and PRAD. The gene discussed is RBP1; the disease is hereditary pheochromocytoma-paraganglioma.