Paired average and tumor tissue data from the TCGA database showed low expression of RBP1 in Bladder Urothelial Carcinoma (BLCA), cholangiocarcinoma (CHOL), esophageal carcinoma (ESCA), head and Neck squamous cell carcinoma (HNSC), kidney renal clear cell carcinoma (KIRC), and prostate adenocarcinoma (PRAD) (Figure 3G). The gene discussed is RBP1; the disease is head and neck squamous cell carcinoma.