SOD1 and diabetic cardiomyopathy: In diabetic animal models, intervention with appropriate antioxidants, such as superoxide dismutase (SOD) mimics or coenzyme Q10, has determined the relationship between oxidative stress and diabetic cardiomyopathy, whether as an early preventive measure to limit the progression of diabetic cardiomyopathy or after the heart has been damaged (12, 13).