Ten differential proteins were identified when comparing CHD and PAH-CHD patients (SAA1 protein, complement Factor H-related Protein 2, anti-Factor VIIIscFv, Carbamoyl-phosphate synthetase I, APCS protein, von-Willebrand factor, BRF1 protein, glyceraldehyde-3-phosphate dehydrogenase, glycosylphosphatidylinositol phospholipase D, and intestinal lactoferrin receptor). This evidence concerns the gene APCS and coronary artery disorder.