EGFR and diabetes mellitus: However, subgroup analysis stratified by treatment type and comorbidity of diabetes mellitus also indicated that the effect of improved PFS was observed only in patients receiving EGFR-TKIs (HR = 0.70, 95% CI: 0.52–0.94, p = 0.019) (Figure 3B) and those with diabetes mellitus (HR = 0.75, 95% CI: 0.61–0.92, p = 0.006) (Figure 3C).