Some information shows that TAM can not only promote angiogenesis and support tumor growth by secreting cytokines such as TGF-β (Dirkx et al., 2006), but also recruit T cells by secreting CCL17 and CCL22 (Qian and Pollard, 2010; McAllister and Weinberg, 2014). This evidence concerns the gene TGFB1 and neoplasm.