ASX nanoemulsions prepared with nanocrystals/nanofibers (CNC/CNF@Nes) combined treatment with low intensity laser can regulate the signal pathway in cancer cells and rely on intracellular signal molecules, such as PI3K, AKT, ERK and EGFR to cause mitochondrial dysfunction, thus inducing apoptosis of cancer cells (Shanmugapriya et al., 2020). The gene discussed is AKT1; the disease is cancer.