SREBF1 and hepatocellular carcinoma: Hepatitis B virus X protein (HBx) activates SREBP1a transcription via C/EBP-α, interacts with LXR-α in HCC cells, and recruits cAMP-response element binding protein (CREB) binding protein to the SREBP1c promoter (Na et al., 2009; Qiao et al., 2013).