Among them, five factors showed significant in a further multivariable analysis, which demonstrated that higher count of CA19-9 (HR, 1.01; 95% CI, 1.00–1.01) and CEA (HR, 1.01; 95% CI, 1.00–1.01), larger tumor size (HR, 1.15; 95% CI, 1.07–1.23), and T2–T4 stage disease (HR, 1.78; 95% CI, 1.15–2.78) were respectively associated with lower odds of survival, whereas well or moderately differentiated tumors (HR, 0.54; 95% CI, 0.34–0.85) were again associated with greater odds of survival (Table 2, Supplementary Figure S2). Here, CEACAM5 is linked to neoplasm.