Meanwhile, the prognosis model outperformed individual prognostic parameters, including CA19-9 (C-index, 0.64; 95% CI, 0.56–0.71), CEA (C-index, 0.59; 95% CI, 0.52–0.65), tumor size (C-index, 0.66; 95% CI, 0.60–0.73), tumor differentiation (C-index, 0.57; 95% CI, 0.52–0.63) and T stage (C-index, 0.57; 95% CI, 0.51–0.63) (Supplementary Figure S3A). Here, CEACAM5 is linked to neoplasm.