GJA1 and infarction: For example, a significant increase in Cx43 levels was found in fibroblasts after myocardial infarction in rats (Miragoli et al., 2006; Vasquez et al., 2010; McArthur et al., 2015), suggesting that increased Cx43 expression in fibroblasts from hearts exposed to infarction may lead to increased formation of gap junctions between myocytes and fibroblasts.