For example, a significant increase in Cx43 levels was found in fibroblasts after myocardial infarction in rats (Miragoli et al., 2006; Vasquez et al., 2010; McArthur et al., 2015), suggesting that increased Cx43 expression in fibroblasts from hearts exposed to infarction may lead to increased formation of gap junctions between myocytes and fibroblasts. The gene discussed is GJA1; the disease is myocardial infarction.