Likewise, we found that the phosphorylation levels of the PTEN/PI3K/AKT/mTOR pathway (Figure 4B) or the expression levels of BDNF/PSD95/synapsin1/snap25 pathway (Figure 4C) remained unchanged between CRS-treated mice and the non-treatment peers. The gene discussed is BDNF; the disease is congenital rubella syndrome.