Strikingly, after sCT treatment, the phosphorylation levels of JNK and p38 in the hippocampus of CRS-treated mice were significantly decreased to a level near the control group (F(2,8) = 9.699, p < 0.05; F(2,9) = 4.602, p < 0.05; Figure 4A), whilst the phosphorylation of ERK1/2, PTEN, PI3K, AKT, mTOR, and the expression of BDNF, PSD95, synapsin-1, snap25 were remained unchanged (Figures 4A–C). The gene discussed is SNAP25; the disease is congenital rubella syndrome.