ANK3 and Behcet disease: Interestingly, lithium has been used to correct BD-related behaviors and neuronal architecture deficits in Ank3 expression-deficient mouse models, suggesting a potential link between ANK3 and the lithium response (Leussis et al., 2013; Gottschalk et al., 2017; Zhu et al., 2017; Piguel et al., 2022).