To our knowledge, few studies have focused on the canonical neuromodulators of CP plasticity and fear-learning in the Fmr1KO BLA, despite neuromodulation strategies (in particular, serotonin receptor modulators) showing promise for reversing behavioral deficits for FXS, ASDs, and NDDs more broadly (Armstrong et al., 2020; Lee et al., 2021; Jeon et al., 2022; Kim et al., 2022). Here, CP is linked to fragile X syndrome.