CD8A and COVID-19: Previous studies using TAME readout showed that the detected frequencies of A24/S448+ and A24/S1208+ CD8+ T cells in COVID-19 individuals are about 6.30~7.71×10-5, which was significantly higher than that of unexposed controls of 8.44~9.50×10-6, suggesting that naive A24/SARS-CoV-2 epitope-specific CD8+ T cells can strongly clone expand about 7.5 folds following COVID-19 (18, 25).