Through univariate analysis and Lasso regression, we screened 13 DRGs (C1QB, CCL4, CD14, CD84, FGL2, MS4A6A, NLRP3, PLEK, RNASE6, SAMSN1, SPN, TMEM176B, ZEB2) related to prognosis in TCGA NSCLC dataset (Supplementary Figure 3). This evidence concerns the gene NLRP3 and non-small cell lung carcinoma.