The results showed that C15orf48 was significantly enriched in high-grade glioma, non-1p/19q deletion state, wild-type, and non- O (6)-methylguanine-DNA-methyltransferase (MGMT) promoter methylated samples in both TCGA and CGGA datasets (Supplementary Figure 2B). The gene discussed is MGMT; the disease is central nervous system cancer.