COXFA4L3 and cancer: In addition, we further evaluated the predictive role of C15orf48 on cancer therapy response using the ROC Plotter database (https://www.rocplot.org/) (28), and the results revealed that C15orf48 was highly expressed in BRCA patients responding to chemotherapy and the AUC value of 5-y recurrence-free survival (RFS) reached 0.645.