We selected the two biomarkers flagged by the ANN (i.e., MPO and PDL1) to look for statistical differences between biomarker concentration and i) the three diseases of our cohort (sepsis, septic shock, and sepsis COVID-19) and ii) the two severity levels our binarization considered (LDMOF and HDMOF) (Figure 6). Here, CD274 is linked to COVID-19.