CD4 and neoplasm: We found that the immune infiltrating cell subpopulations with anti-tumor effects were mainly enriched in the low-risk group, such as the activated dendritic cell and activated CD4/CD8 T cell, while the immunocyte subpopulations with pro-tumor effects were mainly enriched in the high-risk group, such as the myeloid-derived suppressor cells (MDSC) and immature dendric cell.