MOG and demyelinating disease: Similar to MS, myelin oligodendrocyte glycoprotein (MOG)-antibody-associated autoimmune disease (MOGAD) is an inflammatory, demyelinating disease of the CNS with reference to oligodendrocytes, which is primarily characterized by (mostly relapsing) optic neuritis, myelitis and brainstem encephalitis or acute disseminated encephalomyelitis (ADEM) in children (8–11).