As such, Candida worsened Bil Nep mice as indicated by mortality, liver injury (alanine transaminase), serum cytokines (TNF-α, IL-6, and IL-10), leaky gut by FITC-dextran assay, endotoxemia, serum (1➔3)-β-D-glucan (BG), and enterocyte tight junction protein (Zona occludens-1; ZO-1), but not renal injury (blood urea nitrogen and serum creatinine), and bacteremia, when compared with the control Bil Nep using only normal saline solution (NSS) gavage (Figures 1A–O). This evidence concerns the gene TNF and bacterial infectious disease with sepsis.