TJP1 and uremia: The increased endotoxin (LPS) and BG in serum (Figures 1K, L) along with enterocytes damage (ZO-1) (Figures 1N, O) of Bil Nep mice compared with sham mice indicated uremia-induced leaky gut which was more prominent in Candida-administered Bil Nep compared with Bil Nep alone.