CD8A and colorectal cancer: Particular case was reported that the lung metastases in a patient with metastatic colorectal cancer disappeared or shrank after autologous isolation and culture of CD8+ T cells that had a specific effect on the mutant KRAS gene, and were still in a clinically disease-free state four months after surgery (122), which indicated the effectiveness and broad prospect of Trm as an as a potential target of colorectal cancer adoptive cell therapy.