Targeted genes of miR-146a were thus up-regulated and enriched in previews mentioned underline pathogenesis of uveitis such as interferon α/β, interferon γ, Rho GTPases, Miro GTPases, and RHOBTB3, metalloprotease class of deubiquitinases, RUNX1. Here, RHOBTB3 is linked to uveitis.