Moreover, peripheral blood mononuclear cells (PBMCs) IL-23 protein and mRNA levels, serum IL-17 level, IL-17A+ cells in the lamina propria were found to be elevated in several different types of active noninfectious uveitis patients, and IL-23/Th17 pathway cells are thought to be the basis of a common pathophysiology of noninfectious uveitis. The gene discussed is IL17A; the disease is uveitis.