treated mouse models of SS with Labial gland-derived MSCs (LGMSCs)-derived Exos; They reported that LGMSCs and their derived Exos decrease inflammatory cells infiltration to salivary glands and reserve their secretory function in non-obese diabetic (NOD) mice, raise regulatory T cells proliferation and inhibit T helper-cell 17 differentiation in NOD mice and SS patients invitro with increase Tcell secretions of IL-10 and transforming growth factor beta(TGF-β) and decreased cytokine levels(IL-6, IL-17, Interferon-gamma) (85). This evidence concerns the gene IL6 and synovial sarcoma.