TP53 and sarcoma: The incidence of TP53 mutations in ovarian, esophageal, colorectal, head, neck, laryngeal, and lung cancers is 38%–50%, and the mutation rate is approximately 5% in primary leukemia, sarcoma, testicular cancer, malignant melanoma, and cervical cancer, and it is more common in advanced or invasive cancer subtypes (71).