In our article, CCR2 was upregulated in renal tubular tissues of DN than controls and has a high effective diagnostic ability for DN (AUC = 0.859, sensitivity = 77.78%, specificity = 94.59% in a merged dataset; AUC = 0.939, sensitivity = 100.00%, specificity = 90.91%; and AUC = 0.931, sensitivity = 88.89%, specificity = 100.00% in two validation datasets, respectively, GSE175759 and GSE47184; AUC = 0.958, sensitivity = 92.5%, specificity = 96.7% in IHC validation). This evidence concerns the gene CCR2 and liver dysplastic nodule.