When murine AML models are subjected to conditional LSD1 knock out, the same myeloid differentiated immunophenotype is observed, however these cells also gain expression of F4/80, stem cell marker Sca1, and FcεRI, which differs from normal physiological differentiation markers and indicated an atypical differentiation with both features of granulocytic as well as monocytic differentiation (28). Here, KDM1A is linked to acute myeloid leukemia.