CXCL10 and asthma: Azithromycin also inhibits the expression of LPS-induced IFN-inducible protein 10 (IP-10/CXCL10), which is a T helper (Th)1-related chemokine that causes asthma airway inflammation and hypersensitivity through the MAPK-JNK/ERK and NF-κB/p65 pathways (25).