The analysis of CAMK2B mRNA in different stages of colon cancer patients and the analysis of Kaplan-Meier curves of survival corresponding to NFAT1, NFAT2, NFAT3, and NFAT4 expression signatures demonstrated that all these Wnt/Ca2+ elements are overexpressed in advanced colorectal cancer stages, inducing a reduced survival time in patients (please see Supplementary Figure 3). The gene discussed is NFATC3; the disease is malignant colon neoplasm.